Gonadotropin-Releasing Hormone (GnRH)

Gonadotropin-Releasing Hormone (GnRH) is a crucial hormone produced in the hypothalamus of the brain. It plays a central role in regulating reproductive function in both males and females. GnRH acts on the pituitary gland, stimulating the release of two important sex hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

This hormone is essential for sexual development, fertility, and the regulation of the menstrual cycle in women. In men, GnRH is vital for sperm production and testosterone release. It's often referred to as the "master hormone" of reproduction due to its significant influence on the entire reproductive system.

Additional Information

GnRH is released in pulses, with the frequency and amplitude of these pulses varying throughout life and during different stages of the menstrual cycle. This pulsatile release is crucial for normal reproductive function. Disruptions in GnRH production or release can lead to various reproductive disorders, including infertility and hormonal imbalances.

In medical settings, synthetic forms of GnRH (known as GnRH agonists or antagonists) are used to treat various conditions such as prostate cancer, endometriosis, uterine fibroids, and in assisted reproductive technologies like IVF.