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Post-SSRI Sexual Dysfunction

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Post-SSRI Sexual Dysfunction (PSSD) is a condition where sexual side effects persist after discontinuing selective serotonin reuptake inhibitor (SSRI) antidepressants. These ongoing symptoms can include decreased libido, erectile dysfunction, genital numbness, difficulty achieving orgasm, or pleasureless orgasm. PSSD can affect both men and women and may continue for months or years after stopping the medication.

Additional Information

PSSD is not experienced by everyone who takes SSRIs, and its prevalence is not well-established due to limited research. The exact mechanism causing PSSD is not fully understood, but it's thought to involve changes in brain chemistry and sexual functioning. It's important to note that while SSRIs can cause sexual side effects, they are also effective treatments for depression and anxiety for many people.

Individuals experiencing PSSD should consult with their healthcare provider. Treatment options may include switching medications, adjusting dosages, or exploring other therapies to manage symptoms. Some people may find relief through time, while others may need ongoing support and treatment.

Examples

A person notices that their ability to achieve orgasm remains diminished several months after stopping their SSRI medication

Someone experiences persistent low libido even after switching from an SSRI to a different class of antidepressants